Testosterone Cypionate is one of the longest testosterone esters available today. Its half-life in the body is approximately 15 to 16 days (half-life 6-8 days). The drug is available in the form of an oil solution. Due to the fact that it acts for such a long period of time, it can cause water retention to a greater extent than other anabolic steroids. Most often it is used in combined courses for gaining muscle mass.

In the body, Testosterone Cypionate acts like a natural hormone. Testosterone is a male sex hormone that is responsible for many of the physical and emotional qualities of a man. It causes coarsening of the voice, sexual desire, aggression and muscle growth. Testosterone works through anabolic receptors, causing muscles to retain more nitrogen, which in turn is used to create muscle proteins.

The disadvantage of testosterone cypionate is that it aromatizes, or in other words turns into estrogens. When too much estrogen is produced in the male body, feminine traits begin to appear: gynecomastia, water retention, female-type fat deposition, as well as a decrease in sexual desire and testicular atrophy. Most unwanted effects can be prevented if the drug is used correctly.

Many argue that the preference of American athletes is associated not so much with the greater availability of cypionate compared to other esters, but with its greater anabolic effect.The disadvantages of the drug, including fluid retention, can be eliminated with the help of antiestrogens. Testosterone cypionate is especially common in the USA. Although testosterone enanthate is being produced at an increasing rate throughout the world, cypionate is made primarily in the Americas. Therefore, it is not surprising that American athletes most often use it in their practice.

If we compare testosterone cypionate and enanthate objectively, we can conclude that these two steroids are interchangeable, and cypionate is essentially no better. Both long-acting and oil-based, injected. This allows you to maintain high testosterone levels for about two weeks. Enanthate may be more preferable in terms of free form testosterone release, since this ester has one less carbon atom (the duration of the testosterone ester is longer, the longer the ester chain). Despite the heated discussions on the forums, in practice the difference is very insignificant, so the choice may be dictated more by availability than by pharmacological properties.


Like all injectable forms of testosterone, cypionate causes a significant increase in muscle mass and strength during the cycle. Since testosterone is easily converted to estrogen, approximately 30% of the mass will be fluid, which is quickly lost after the end of the cycle.

For the same reason, testosterone cypionate is not very suitable for a cycle. The excess estrogen levels caused by this drug can quickly lead to the development of gynecomastia, which manifests itself as soreness, swelling or induration in the nipples. To prevent this, auxiliary drugs (Nolvadex or Clomid) are used.Antiestrogens minimize the effects of estrogen, and bring the action of anabolic steroids into a directed direction. It is best to use aromatase blockers.

Since testosterone is the main male androgen, significant androgenic side effects can also be expected. In many ways, their severity is related to the rate at which testosterone in the body turns into dihydrotestosterone (DHT). This substance is a metabolite of testosterone, which is responsible for the development of known androgenic effects that are associated with the use of testosterone cypionate. These include: increased secretion of sebum, acne, hair growth on the body and face, as well as male pattern baldness.

Hair loss on the head is not expressed in everyone. First of all, those who have a genetic predisposition (a case of baldness in the family) should worry about this. To prevent this side effect, you can use the drug Propecia (Proscar), which blocks the conversion of testosterone to dihydrotestosterone. Propecia significantly reduces the risk of alopecia, and also reduces the likelihood of other androgenic effects.


Despite the fact that the duration of the drug is quite long, injections are performed once a week to keep the concentration constantly high.

The average single dose is 250-500 mg per week, in order to gain muscle mass. The drug gives good results during the course "solo". Practice shows that doses above 800-1000 mg do not lead to better results, but the risk of side effects increases dramatically.

As noted above, to block the action of estrogens, it is necessary to use Tamoxifen (10 mg per day, starting from the second week of the cycle and ending its intake 2 weeks after the end of testosterone intake). A more preferred option: use during the course of Proviron. After the end of testosterone administration, Proviron should be replaced with Tamoxifen to restore the secretion of one's own testosterone. The use of antiestrogens reduces the accumulation of fluid in the body, and also inhibits the development of gynecomastia. Be sure to read the article on PCT.

If the duration of the course exceeds 4 weeks, it is necessary to use gonadotropin 500 IU, 1 time per week during the entire course, starting from the 3rd week.

Combined course

The combined course of testosterone cypionate is not much different from the "solo". The drug is most often combined with Nandrolone at a dose of 200 mg per week. The dosage of cypionate is on average 200 mg per week.