Description

Clenbuterol buy , being a beta-2 agonist, acts as a fat burner by binding to type 2 beta receptors in adipose and muscle tissue of the human body. After clenbuterol binds to the receptor, a cascade of biochemical reactions is launched that leads to an increase in the synthesis of cAMP (cyclic adenosine monophosphate). cAMP in turn activates enzymes that mobilize fatty acids from adipocytes (adipose tissue cells).
Anabolic and anti-catabolic effects of clenbuterol
Under the action of clenbuterol on the beta-2-adrenergic receptors of the presynaptic membrane, the release of norepinephrine and adrenaline increases, which have a powerful fat-burning effect. Clenbuterol buy Ukraine increases the level of basic metabolism by 20-30% of the original level.
Clenbuterol price inhibits the activity of lipoprotein lipase, as a result of which the deposition of fat in adipose tissue becomes impossible. Acting on the beta-2-adrenergic receptors of the central nervous system, this drug enhances the secretion of thyroid hormones – the body's natural fat burners.
A unique feature of clenbuterol is that it is not only a powerful fat burner, but also has a pronounced anti-catabolic effect, protecting muscles from destruction, which is very important during weight loss and drying in bodybuilding. In studies, it was found that the anti-catabolic effect of the drug is due to the blocking of Ca ++ dependent and ubiquitin-proteasome proteolysis.
A new 2012 study (Francesca Wannenes, Loretta Magni) confirms the ability of clenbuterol to block the mechanisms of muscle atrophy.
Due to the above mechanisms, the drug has a moderate anabolic effect, which has been proven in animal experiments and practical use in bodybuilding. Some authors (Yury Bombela) claim that in high doses clenbuterol can have catabolic effects, but this statement is not true. There is no physiological or practical justification for this.
Given the fact that the drug has little to no interaction with beta-1-adrenergic receptors, there is bronchial dilation and easier breathing, as well as a much lower incidence of side effects from the cardiovascular system, compared with non-selective agonists such as ephedrine.
How to use:
In men, the recommended dose of clenbuterol for cutting and losing weight is 120-140 mcg per day. In women, the average dose of clenbuterol for drying and weight loss is 80-100 mcg per day. The course of clenbuterol has its own subtle features that must be strictly observed in order to avoid side effects.
The duration of the course of clenbuterol is usually 2 weeks, then addiction (receptor tolerance) is developed and the effectiveness decreases. After that, you need to take a 2-week break and then repeat the course. The duration and effectiveness of the course of clenbuterol can be increased by the inclusion of ketotifen. Sometimes, to prevent the adaptation of receptors, a pulse course is recommended – 2 days of admission, 2 days of rest, but this scheme is less effective.
Remember to take in enough protein, BCAAs, and other cortisol blockers during your cycle to greatly improve your results. Follow an appropriate diet for weight loss or drying.
In 2010, a study was conducted that revealed a synergistic effect when combined with anabolic steroids, which confirms the advisability of including the drug at the end of the AS course
Effects:
Fat burning and muscle drying
Temperature rise
Decreased appetite
Psychic activation
Anti-catabolic action
Anabolic action (weakly expressed)
The low frequency of side effects, the almost complete absence of harm to health (practice shows that irreversible side effects are almost completely absent) and a wide range of positive effects make clenbuterol one of the best fat burners in bodybuilding.